Targeson develops, manufactures and markets ultrasound imaging agents for perfusion and molecular imaging applications in the research market.
Targeson’s molecular targeted agents are gas-encapsulated microspheres that, when coated with specific targeting ligand molecules, can adhere to molecular markers of disease. This technique can be used in animal models of a wide variety of diseases, such as cancer, heart attack, atherosclerosis and cardiovascular plaque, organ transplant rejection, and inflammatory bowel disease.
Targeson’s commercial products include:
Targestar® P,Perfusion contrast agent to enhance and quantify blood flow and vascular function.
Targestar P-HF,Perfusion contrast agent for use with high frequency scanners for blood flow and vascular function.
Targestar SA,Targetable contrast agent enabling a biotinylated antibody/biomolecule to be coupled to a microsphere.
Visistar® Integrin,Targeted contrast agent that binds integrin for imaging angiogenesis and tumor growth.
Visistar VEGFR2,Targeted contrast agent with a VEGFR2 binding ligand for imaging angiogenesis and tumor growth.
Visistar VCAM-1,Targeted contrast agent targeted to VCAM-1 for molecular imaging of inflammation.
Targesphere™,Cationic delivery agent used for in vivo and in vitro transfection.
Targestar ® Visistar VCAM-1
Wash-in and accumulation of Visistar VCAM-1 in plaque-containing arteries in mouse model of atherosclerosis.
