News

Contrast Ultrasound Imaging

Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow.

Klibanov AL, Rychak JJ, Yang WC, Alikhani S, Li B, Acton S, Lindner JR, Ley K, Kaul S. Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imaging. 2006 Nov;1(6):259-66.

Microultrasound molecular imaging of vascular endothelial growth factor receptor 2 in a mouse model of tumor angiogenesis.

Rychak JJ, Graba J, Cheung AM, Mystry BS, Lindner JR, Kerbel RS, Foster FS. Microultrasound molecular imaging of vascular endothelial growth factor receptor 2 in a mouse model of tumor angiogenesis. Mol Imaging. 2007 Sep-Oct;6(5):289-96.

Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin

Lindner JR, Song J, Christiansen J, Klibanov AL, Xu F, Ley K. Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation. 2001 Oct 23;104(17):2107-12.

Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alpha(v)-integrins

Leong-Poi H, Christiansen J, Klibanov AL, Kaul S, Lindner JR. Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alpha(v)-integrins. Circulation. 2003 Jan 28;107(3):455-60.

Assessment of endogenous and therapeutic arteriogenesis by contrast ultrasound molecular imaging of integrin expression

Leong-Poi H, Christiansen J,Heppner P, Lewis CW, Klibanov AL, Kaus S, Lindner JR. Assessment of endogenous and therapeutic arteriogenesis by contrast ultrasound molecular imaging of integrin expression. Circulation. 2005 Jun 21; 111(224):3248-54.

Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow

Takalkar AM, Klibanov AL, Rychak JJ, Lindner JR, Ley K. Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow. J Control Release. 2004 May 18;96(3):473-82.

Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn’s disease.

Bachmann C, Klibanov AL, Olson TS, Sonnenschein JR, Rivera-Nieves J, Cominelli F, Ley KF, Lindner JR, Pizarro TT. Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn’s disease. Gastroenterology. 2006 Jan;130(1):8-16.

Deformable gas-filled microbubbles targeted to P-selectin.

Rychak JJ, Lindner JR, Ley K, Klibanov AL. Deformable gas-filled microbubbles targeted to P-selectin. J Control Release. 2006 Sep 12; 114: 288-299.

Selectin ligands promote ultrasound contrast agent adhesion under shear flow.

Rychak JJ, Li B, Acton ST, Leppanen A, Cummings RD, Ley K, Klibanov AL. Selectin ligands promote ultrasound contrast agent adhesion under shear flow. Mol Pharm. 2006 Sep-Oct; 3: 516-524.